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Updated: Aug 2, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Effect of delayed sample draw after blood collection for haemoglobin test in South Korea
1Department of Laboratory Medicine, Pusan National University Hospital, Busan, Republic of Korea.
Abstract:
Between April and May 2022, 10 healthy adult non-patients were recruited from Pusan National University Hospital. Venous blood drawn into a syringe was transferred into test tubes with a zero-to-45-minute delay. The transfer was done sequentially in two positions with the syringe and the needle adaptor end (1) heading downwards and (2) heading upwards. Haemoglobin levels gradually increased over time in position 1 transfer while they gradually decreased in position 2. Therefore, blood must be transferred quickly from a syringe to a tube for reliable test results.
What This Study Adds:
Our findings confirm that delays between blood collection and transfer can affect haemoglobin levels.
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