Case report: Obstructive jaundice caused by biliary cystadenoma.

Area of Science:

• Hepatobiliary surgery
• Gastroenterology
• Oncology

Background:

• Biliary cystadenoma, also known as mucinous cystic neoplasm with low-grade intraepithelial neoplasia, is a rare cystic tumor originating from the biliary epithelium.
• The etiology of biliary cystadenoma remains unclear, posing diagnostic challenges.

Observation:

• A 56-year-old woman presented with jaundice, poor appetite, and epigastric pain, with elevated total bilirubin and carbohydrate antigen 19-9 (CA19-9).
• Imaging revealed a large intrahepatic cystic lesion with common bile duct dilation and thickening, suggestive of either biliary cystadenoma or malignancy.

Findings:

• Histopathology confirmed a mucinous cystadenoma of the liver and hilar bile duct.
• The tumor presented macroscopically as a polypoid mass extending along the bile duct and a cystic-solid mass in the liver.

Implications:

• This case underscores the importance of considering biliary cystadenoma in the differential diagnosis of intrahepatic cystic lesions presenting with jaundice.
• Accurate diagnosis and surgical resection are crucial for managing biliary cystadenoma, despite its rarity and potential for diagnostic ambiguity.