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Mucocutaneous Manifestations in Kidney Transplant Patients: Risk Factors
Yasmina El Arabi1, Fouzia Hali1, Yasmine Mahdar1
1Dermatology, Ibn Rochd University Hospital, Casablanca, MAR.
Cureus
|April 17, 2023
Summary
Kidney transplant patients face mucocutaneous complications, often infectious. Risk factors include older age, male gender, anemia, non-identical donors, and specific immunosuppressants like Tacrolimus and Thymoglobulin.
Area of Science:
- Nephrology
- Dermatology
- Immunology
Background:
- Kidney transplant recipients frequently experience mucocutaneous complications.
- These complications are often linked to drug toxicity and immunosuppression.
- Identifying risk factors is crucial for patient management.
Purpose of the Study:
- To determine the risk factors associated with mucocutaneous complications in kidney transplant patients.
- To analyze the characteristics of patients developing these complications.
Main Methods:
- A prospective analytical study was conducted from January 2020 to June 2021.
- 86 kidney transplant patients were recruited and analyzed.
- Statistical analysis identified significant risk factors (p<0.05).
Main Results:
- Thirty patients (34.9%) developed mucocutaneous complications.
- Infectious manifestations (53.4%) were most common, followed by inflammatory ones (36.6%).
- Advanced age, male gender, anemia, HLA non-identical donor, Tacrolimus, and Thymoglobulin were significant risk factors.
Conclusions:
- Infectious mucocutaneous complications are prevalent in renal transplant recipients.
- Key risk factors include advanced age, male gender, anemia, HLA non-identical donor, Tacrolimus, and Thymoglobulin.
- Early identification and management of these factors can improve patient outcomes.
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