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Updated: Aug 2, 2025

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
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Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis

Published on: February 24, 2023

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Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis?

Ananyan Sampath1, M Sukumar1, Penuboina Tejaswini1

  • 1General Medicine, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

Cureus
|April 17, 2023
PubMed

Insights

Melioidosis, a severe disease caused by Burkholderia pseudomallei, is increasingly reported in India. Early diagnosis and treatment are crucial for patient recovery.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Melioidosis is a severe, potentially fatal disease caused by Burkholderia pseudomallei.
  • Endemic in Southeast Asia and Northern Australia, with rising cases in India.
  • B. pseudomallei is suspected to originate from soil and water in India, with skin contact as the primary infection route.

Observation:

  • A 55-year-old female in India presented with acute febrile illness and progressive dyspnea.
  • Clinical worsening necessitated intensive care unit (ICU) admission.
  • The patient's symptoms mimicked acute pneumonia.

Findings:

  • The case was diagnosed as melioidosis, a condition with varied clinical presentations in India, complicating diagnosis.
  • Treatment involved antibiotics and supportive care.
  • Rapid recovery was observed following treatment.

Implications:

  • Highlights the need for increased awareness and a high index of suspicion for melioidosis in the Indian subcontinent.
  • Emphasizes the importance of early diagnosis for improving patient outcomes.
  • Underscores the diagnostic challenges posed by the varied clinical manifestations of melioidosis in India.
Keywords:
acute pneumoniaartificial intelligenceburkholderiachatgptfevermelioidosis

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