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The Effect of Percutaneous Coronary Intervention on QT Dispersion and the Association Between Them: A Systematic

Mahdi Dahrab1, Sai Pranathi Gaddipati2, Keval B Patel3

  • 1Internal Medicine, McMaster University, Hamilton, CAN.

Cureus
|April 17, 2023
PubMed

Insights

Percutaneous coronary intervention (PCI) significantly reduces QT dispersion (QTd) and corrected QT (QTc) intervals. This systematic review confirms PCI

Area of Science:

  • Cardiology
  • Medical Imaging
  • Clinical Research

Background:

  • Electrocardiography (ECG) parameters are crucial for diagnosing ischemia and cardiovascular diseases.
  • Reperfusion therapies are vital for restoring blood flow to ischemic tissues.

Purpose of the Study:

  • To investigate the association between percutaneous coronary intervention (PCI) and the ECG parameter QT dispersion (QTd).

Main Methods:

  • A systematic review of 3,626 studies was conducted across ScienceDirect, PubMed, and Google Scholar.
  • 12 studies involving 1,239 patients met the inclusion criteria.
  • Statistical analysis was performed using Review Manager (RevMan) 5.4.

Main Results:

  • Successful PCI procedures led to significant reductions in QT dispersion (QTd) and corrected QT (QTc) intervals.
  • These reductions were observed at various time points post-intervention.
  • A clear association was found between PCI and decreased QTd, QTc, and corrected QT dispersion (QTcd).

Conclusions:

  • PCI is associated with a considerable reduction in key ECG parameters, including QTd, QTc, and QTcd.
  • This suggests PCI positively impacts ventricular repolarization dynamics.
  • ECG parameters like QTd may serve as indicators of successful PCI outcomes.

Keywords:
angioplasty and stentingcorrected qt intervalecg abnormalitiesprimary percutaneous coronary intervention (pci)qt dispersion

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