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New steroidal saponins from the roots of Paris verticillata
Yang Liu1, Na Tang2, Xiao-Ying Qian3
1Department of Pharmaceutics, School of Pharmacy, Air Force Medical University, Xi'an, China.
Abstract:
Four new polyhydroxylated steroidal saponins, parisverticillatosides A-D (1-4), together with four known spirostanol saponins (5-8) were isolated from the roots of Paris verticillata. Their structures were elucidated on the basis of extensive spectroscopic analysis and chemical evidences. The discovery of the new compounds 1-4 extended the diversity and complexity of this spirostanol saponin family. The saponins 5 and 6 exhibited cytotoxicities against two human glioma cell lines.
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