Related Experiment Video
Updated: Aug 2, 2025

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
Contemporary Diagnosis and Management of Patients with MINOCA
Purvi Parwani1,2, Nicolas Kang3,4, Mary Safaeipour3,4
1Division of Cardiology, Department of Medicine, Loma Linda University Health, Loma Linda, CA, USA. pparwani@llu.edu.
Purpose Of Review:
Myocardial infarction with nonobstructive coronary arteries (MINOCA) is defined as acute myocardial infarction (MI) with angiographically no obstructive coronary artery disease or stenosis ≤ 50%. MINOCA is diagnostically challenging and complex, making it difficult to manage effectively. This condition accounts for 6-8% of all MI and poses an increased risk of morbidity and mortality after diagnosis. Prompt recognition and targeted management are essential to improve outcomes and our understanding of this condition, but this process is not yet standardized. This article offers a comprehensive review of MINOCA, delving deep into its unique clinical profile, invasive and noninvasive diagnostic strategies for evaluating MINOCA in light of the lack of widespread availability for comprehensive testing, and current evidence surrounding targeted therapies for patients with MINOCA.
Recent Findings:
MINOCA is not uncommon and requires comprehensive assessment using various imaging modalities to evaluate it further. MINOCA is a heterogenous working diagnosis that requires thoughtful approach to diagnose the underlying disease responsible for MINOCA further.
More Related Videos
Related Concept Videos
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Mitral Stenosis III: Medical Management
Chronic Pancreatitis II: Collaborative Care
Assessment:
Acute Coronary Syndrome IV: Interprofessional Care
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
Rheumatic Heart Disease III: Medical Management

