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Updated: Aug 2, 2025
08:08
Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model
Published on: June 18, 2013
17.4K
Maternal implications of placental transfusion
Katelyn Uribe1, Arpitha Chiruvolu2, Angie C Jelin1
1Department of Gynecology and Obstetrics, Division of Maternal-Fetal Medicine, Johns Hopkins School of Medicine, 600 N. Wolfe Street, Phipps 228, Baltimore, MD 228, USA.
Seminars in Perinatology
|April 17, 2023
Summary
Delayed umbilical cord clamping, or placental transfusion, benefits newborns with minimal maternal risk. This practice is recommended for routine use, ensuring neonatal well-being without increasing maternal complications like postpartum hemorrhage.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Medicine
Background:
- Delayed umbilical cord clamping (30-60 seconds) is a widely adopted practice.
- It is recommended by numerous professional societies for neonatal benefits.
Purpose of the Study:
- To evaluate the maternal and neonatal outcomes associated with delayed umbilical cord clamping.
- To assess the safety and efficacy of placental transfusion.
Main Methods:
- Review of existing studies on delayed cord clamping and placental transfusion.
- Analysis of maternal outcomes including postpartum hemorrhage and blood transfusion needs.
- Assessment of neonatal benefits and potential risks.
Main Results:
- Delayed cord clamping demonstrates significant neonatal benefits.
- No increased incidence of postpartum hemorrhage or need for blood transfusion in mothers.
- Potential decrease in fetomaternal hemorrhage.
- Umbilical cord milking has limited supporting data and adoption.
Conclusions:
- Delayed umbilical cord clamping (placental transfusion) is advised for neonatal benefit.
- The practice poses minimal maternal risk, even in vaginal delivery or cesarean section.
- Individualized cord management is necessary for fetal anomalies, without significant maternal morbidity.
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