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Updated: Aug 2, 2025
06:07
Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
Published on: June 13, 2020
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Probiotics as a Therapeutic Approach in Colorectal Cancer
Nafiseh Rahmani1, Ghazaleh Pourali2, Nayyerehalsadat Hosseini3
1Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Current Cancer Drug Targets
|April 18, 2023
Summary
Probiotics show promise in preventing and treating colorectal cancer (CRC), offering a potentially effective therapeutic approach. Research explores their mechanisms and clinical effectiveness in managing CRC and its complications.
Area of Science:
- Gastroenterology
- Oncology
- Microbiology
Background:
- Colorectal cancer (CRC) incidence is rising globally, linked to lifestyle factors like poor diet and inactivity.
- Increased CRC rates necessitate novel prevention and treatment strategies with improved efficacy and reduced complications.
- Probiotics are emerging as a promising therapeutic avenue for CRC management.
Conclusions:
- Probiotics represent a promising therapeutic strategy for colorectal cancer, with potential benefits in prevention, treatment, and complication management.
- Further research into specific probiotic strains and combinations is crucial for optimizing their use in CRC therapy.
- Lifestyle modifications alongside probiotic interventions may offer a comprehensive approach to combating colorectal cancer.
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