Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CARI-7A: DEVELOPMENT AND VALIDATION.

Radiation protection dosimetry·2017
Same author

A new equation for calculating the maximum wait time for pilots who use an impairing medication.

Aviation, space, and environmental medicine·2014
Same author

Effects of fluid load on human urine characteristics related to workplace drug testing.

Journal of analytical toxicology·2012
Same author

Drugs and alcohol found in civil aviation accident pilot fatalities from 2004-2008.

Aviation, space, and environmental medicine·2012
Same author

Comparison of fluence-to-dose conversion coefficients for deuterons, tritons and helions.

Radiation protection dosimetry·2011
Same author

Helions at energies of 10 MeV to 1 TeV: conversion coefficients for fluence-to-absorbed dose, equivalent dose, effective dose and gray equivalent, calculated using Monte Carlo radiation transport code MCNPX 2.7.C.

Radiation protection dosimetry·2010
Same journal

Incidental Renal Cell Carcinoma in an Active-Duty Fighter Pilot.

Aerospace medicine and human performance·2026
Same journal

Large Language Models as Behavioral Health Teammates in Long-Duration Spaceflight.

Aerospace medicine and human performance·2026
Same journal

Long-Term Post-Bariatric Surgical Outcomes for Aeromedical Certification Consideration.

Aerospace medicine and human performance·2026
Same journal

Middle Ear and Sinus Barotraumas of Military Pilots in Finland.

Aerospace medicine and human performance·2026
Same journal

From Humanitarian Airlifts to Neonatal Intensive Care in the Sky.

Aerospace medicine and human performance·2026
Same journal

Cognitive Performance During Acute Hypoxia Is Associated with Cerebral Oxygenation and Blood Flow.

Aerospace medicine and human performance·2026
See all related articles

Related Experiment Video

Updated: Aug 2, 2025

MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges
09:33

MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges

Published on: December 17, 2014

14.1K

Cerebral Blood Flow Based Computer Modeling of Gz-Induced Effects.

Kyle Copeland, James E Whinnery

    Aerospace Medicine and Human Performance
    |April 18, 2023
    PubMed
    Summary
    This summary is machine-generated.

    A new software model accurately predicts G-induced loss of consciousness (G-LOC) and other physiological effects in pilots. This tool helps assess risks from factors like fatigue and countermeasures in aviation.

    More Related Videos

    Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo
    06:24

    Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo

    Published on: July 8, 2025

    335
    Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
    07:21

    Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

    Published on: May 27, 2022

    3.2K

    Related Experiment Videos

    Last Updated: Aug 2, 2025

    MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges
    09:33

    MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges

    Published on: December 17, 2014

    14.1K
    Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo
    06:24

    Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo

    Published on: July 8, 2025

    335
    Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
    07:21

    Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

    Published on: May 27, 2022

    3.2K

    Area of Science:

    • Aerospace Medicine
    • Human Factors Engineering
    • Physiological Modeling

    Background:

    • Acceleration (G) effects are critical in aviation accidents, impacting consciousness and vision.
    • G-induced loss of consciousness (G-LOC) and related phenomena pose risks in military, aerobatic, and agricultural aviation.
    • Understanding G-effects is vital for flight safety and accident investigation.

    Purpose of the Study:

    • To develop and validate a software model for evaluating G-LOC risk in aeronauts.
    • To assess the impact of various physiological and equipment factors on G-tolerance.
    • To provide a tool for understanding risk changes due to fatigue, medications, and countermeasures.

    Main Methods:

    • Developed the Civil Aerospace Medical Institute G-Effects Model (CGEM) using physical and physiological variables.
    • Modeled aeronauts with parameters including sex, fitness, G-suits, and breathing gear.
    • Validated the CGEM against experimental data from peer-reviewed literature and centrifuge studies.

    Main Results:

    • CGEM accurately predicted physiological Gz exposure effects, especially for rapid onset rates.
    • Predicted G-LOC times and incapacitation periods were within 1 SD of experimental results from USN and USAF pilots.
    • Model predictions for visual effects onset and aerobatic maneuver symptoms aligned with published data.

    Conclusions:

    • CGEM is a valuable new tool for civil and military aviation safety.
    • The model offers insights into risk changes from factors like fatigue, medications, and anti-G countermeasures.
    • Flight surgeons, pilots, and investigators can utilize CGEM for better risk assessment beyond simple G-tolerance values.