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Creatine phosphate improves myocardial function and myocardial enzyme profile in children with myocarditis

Shaoli Lin1, Junbo Yang2, Jing Yu3

  • 1Department of Pediatrics, Yantaishan Hospital, Yantai, China.

Biotechnology & Genetic Engineering Reviews
|April 18, 2023
PubMed

Insights

Creatine phosphate effectively treats pediatric myocarditis, improving heart function and reducing myocardial damage in children. This treatment offers a safe and beneficial option for improving cardiac outcomes.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Pharmacology

Background:

  • Myocarditis in children can lead to significant cardiac dysfunction.
  • Effective therapeutic strategies for pediatric myocarditis are crucial.

Purpose of the Study:

  • To evaluate the efficacy and safety of creatine phosphate in treating pediatric myocarditis.
  • To compare creatine phosphate treatment with standard care in children with myocarditis.

Main Methods:

  • A comparative study involving two groups of children diagnosed with myocarditis.
  • The observation group received creatine phosphate in addition to sodium fructose diphosphate.
  • The control group received only sodium fructose diphosphate.

Main Results:

  • Children treated with creatine phosphate showed improved myocardial enzyme profiles.
  • Cardiac function was significantly better in the creatine phosphate group compared to the control group.
  • The overall treatment effective rate was higher in the observation group.

Conclusions:

  • Creatine phosphate demonstrates significant benefits in improving myocardial function and reducing cardiac damage in pediatric myocarditis.
  • The treatment exhibits a high safety profile, supporting its clinical applicability.
  • Creatine phosphate is a promising therapeutic agent for pediatric myocarditis, warranting further clinical promotion.

Keywords:
Creatine phosphateinflammatory factorsmyocardial injurymyocarditis of childrensodium fructose diphosphate

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