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Paralytic shellfish poisoning in Singapore.

C T Tan, E J Lee

    Annals of the Academy of Medicine, Singapore
    |January 1, 1986
    PubMed
    Summary

    The first reported outbreak of paralytic shellfish poisoning in Singapore involved toxic green mussels, leading to two fatalities. Mouse bioassays confirmed the presence of toxins, highlighting the public health risk of red tide events.

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    Area of Science:

    • Marine Biology
    • Toxicology
    • Public Health

    Background:

    • Paralytic shellfish poisoning (PSP) is a severe illness caused by consuming shellfish contaminated with toxins from dinoflagellates.
    • Red tide events, characterized by high concentrations of toxic algae, pose a significant risk to marine ecosystems and human health.

    Observation:

    • This paper documents the inaugural outbreak of PSP linked to green mussels in Singapore.
    • The outbreak tragically resulted in two human deaths, underscoring the severity of the poisoning.

    Findings:

    • Standardized mouse bioassays conclusively identified the presence of PSP toxins in the affected mussel meat.
    • Researchers explored extending the mouse bioassay to analyze gastrointestinal contents for toxin detection.

    Implications:

    • This event highlights the critical need for robust monitoring of shellfish toxicity and red tide phenomena in Singapore.
    • Effective public health advisories and rapid response protocols are essential to prevent future PSP-related fatalities.

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