Allergen detection and logistic multifactor analysis of allergic rhinitis

Area of Science:

• Pediatrics
• Allergology
• Environmental Health

Background:

• Allergic rhinitis (AR) is a common condition in children.
• Identifying specific allergens and risk factors is crucial for effective management.

Purpose of the Study:

• To investigate common allergens in children diagnosed with allergic rhinitis (AR).
• To identify influencing factors and risk factors associated with AR in children.

Main Methods:

• Retrospective analysis of clinical data from 230 children with AR and 230 healthy controls.
• Allergen testing using serum allergens and data collection via telephone questionnaires.
• Univariate and multivariate logistic regression analyses to determine risk and protective factors.

Main Results:

• House dust mite (75.22%) and shrimp (40.87%) were the most prevalent inhaled and food allergens, respectively.
• Risk factors identified include asthma, second-hand smoke exposure, floating population status, recent home decoration, family history of AR, and presence of domestic animals.
• Daily ventilation and cleaning emerged as protective factors against AR incidence.

Conclusions:

• House dust mite and shrimp are significant allergens in pediatric AR.
• Asthma, environmental exposures (second-hand smoke, decoration), family history, and pets are key risk factors.
• Implementing measures like regular ventilation and cleaning can mitigate AR occurrence and recurrence.