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Progressive multifocal leukoencephalopathy and magnetic resonance imaging
Annals of Neurology
|April 1, 1986
Abstract:
Progressive multifocal leukoencephalopathy developed in a homosexual man with underlying Hodgkin's disease. Computed tomography and magnetic resonance imaging of the brain demonstrated multiple lesions, more in gray than white matter. Brain biopsy established the diagnosis of progressive multifocal leukoencephalopathy. Magnetic resonance imaging was found useful for detecting brain lesions and for localizing an accessible lesion for biopsy.
Insights
Progressive multifocal leukoencephalopathy (PML) occurred in a man with Hodgkin
Area of Science:
- Neurology
- Oncology
- Infectious Diseases
Background:
- Progressive multifocal leukoencephalopathy (PML) is a rare, fatal demyelinating disease.
- PML is caused by the JC virus, often seen in immunocompromised individuals.
- Hodgkin's disease is a cancer of the lymphatic system that can impair immune function.