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Updated: Aug 2, 2025

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Scoping review of guidance on cessation interventions for electronic cigarettes and dual electronic and combustible
Anasua Kundu1, Erika Kouzoukas2, Laurie Zawertailo2
1Institute of Medical Science (Kundu), University of Toronto; Centre for Addiction and Mental Health (Kouzoukas, Zawertailo, Fougere, Dragonetti, Selby, Schwartz); Departments of Pharmacology and Toxicology (Zawertailo), and Family and Community Medicine (Dragonetti, Selby), and Dalla Lana School of Public Health (Schwartz), University of Toronto, Toronto, Ont. anasua.kundu@mail.utoronto.ca.
Background:
Although evidence-based smoking cessation guidelines are available, the applicability of these guidelines for the cessation of electronic cigarette and dual e-cigarette and combustible cigarette use is not yet established. In this review, we aimed to identify current evidence or recommendations for cessation interventions for e-cigarette users and dual users tailored to adolescents, youth and adults, and to provide direction for future research.
Methods:
We systematically searched MEDLINE, Embase, PsycINFO and grey literature for publications that provided evidence or recommendations on vaping cessation for e-cigarette users and complete cessation of cigarette and e-cigarette use for dual users. We excluded publications focused on smoking cessation, harm reduction by e-cigarettes, cannabis vaping, and management of lung injury associated with e-cigarette or vaping use. Data were extracted on general characteristics and recommendations made in the publications, and different critical appraisal tools were used for quality assessment.
Results:
A total of 13 publications on vaping cessation interventions were included. Most articles were youth-focused, and behavioural counselling and nicotine replacement therapy were the most recommended interventions. Whereas 10 publications were appraised as "high quality" evidence, 5 articles adapted evidence from evaluation of smoking cessation. No study was found on complete cessation of cigarettes and e-cigarettes for dual users.
Interpretation:
There is little evidence in support of effective vaping cessation interventions and no evidence for dual use cessation interventions. For an evidence-based cessation guideline, clinical trials should be rigorously designed to evaluate the effectiveness of behavioural interventions and medications for e-cigarette and dual use cessation among different subpopulations.
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