The application of genome editing technology in fish

Area of Science:

• Life Sciences
• Molecular Biology
• Aquaculture

Background:

• Genome editing technologies have advanced significantly in the last decade.
• Zinc finger nucleases (ZFN), transcription activator like effector nucleases (TALEN), and CRISPR are key genome editing tools.
• Ongoing research aims to develop more efficient and accurate genome editing techniques.

Purpose of the Study:

• To review the applications of genome editing technologies in fish species.
• To detail the impact on fish growth, gender, and pigmentation traits.
• To highlight the use of genome editing in zebrafish disease modeling and functional gene screening.

Main Methods:

• Review of existing literature on genome editing in fish.
• Focus on applications in aquaculture and basic research.
• Analysis of specific trait modifications and disease model construction.

Main Results:

• Genome editing has been extensively applied across various fish species.
• Applications include modification of growth, gender, and pigmentation traits.
• Zebrafish disease models and high-throughput gene screening have been successfully developed.

Conclusions:

• Genome editing technologies offer powerful tools for fish research and aquaculture.
• Future perspectives include further improvements in editing efficiency and accuracy.
• These advancements hold significant potential for both scientific understanding and practical applications in fish.