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POEM from A to Z: current perspectives.
Eduardo Albéniz1, Carlos Marra-López Valenciano2, Fermín Estremera-Arévalo3
1Endoscopy Unit. Gastroenterology, Hospital Universitario de Navarra (HUN). Navarrabiomed. UPNA. IdiSNA, España.
Third space endoscopy, also known as submucosal endoscopy, offers minimally invasive treatments for various gastrointestinal conditions. This technique, including peroral endoscopic myotomy (POEM), is expanding globally for motility disorders and tumors.
Area of Science:
- Gastroenterology and Endoscopic Surgery
- Minimally Invasive Therapeutic Endoscopy
Background:
- Third space endoscopy, or submucosal endoscopy, has been clinically available since 2010.
- It involves accessing the submucosa and deeper gastrointestinal layers via tunneling techniques.
Purpose of the Study:
- To review the current applications and evolving landscape of third space endoscopy.
- To highlight its potential as a standard treatment for various GI pathologies.
Main Methods:
- Utilizes modified submucosal tunneling techniques for endoscopic access.
- Includes peroral endoscopic myotomy (POEM) and its variants.
Main Results:
- Enables treatment of achalasia, esophageal motility disorders, diverticula, and subepithelial tumors.
- Demonstrates potential for treating gastroparesis, esophageal strictures, and pediatric conditions like Hirschsprung's disease.
Conclusions:
- Third space endoscopy procedures are increasingly adopted worldwide.
- Despite ongoing standardization, these techniques are poised to become the standard of care for numerous gastrointestinal conditions.
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