Related Experiment Video
Updated: Aug 2, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Designing a Multilevel Strategy to Enhance Secondary Prevention of Heart Disease
Karen Tenner1, Anita Rao2, Yoni Dvorkis3
1Department of Family Medicine, Atrius Health, Newton, MA, USA.
Insights
Incidental coronary artery calcification (CAC) found on noncardiac scans is common. Implementing standardized guidelines improved statin prescribing for secondary prevention of coronary artery disease (CAD).
Area of Science:
- Cardiology
- Radiology
- Public Health
Background:
- Coronary artery calcification (CAC) is a strong predictor of coronary artery disease (CAD).
- Incidental CAC findings on noncardiac imaging are often overlooked by primary care clinicians.
- This represents a missed opportunity for secondary CAD prevention.
Purpose of the Study:
- To develop and implement standardized practice guidelines for managing incidental CAC.
- To improve secondary prevention of cardiovascular disease through incidental CAC identification.
- To evaluate the impact of these guidelines on statin prescribing behaviors.
Main Methods:
- An interdisciplinary committee developed evidence-based practice guidelines.
- A multilevel implementation strategy integrated guidelines into electronic medical records.
- Retrospective review of noncardiac CT scans before and after the initiative assessed statin prescribing.
Main Results:
- Statin prescribing increased for patients with mild CAC.
- High-intensity statin prescribing increased for patients with severe CAC.
- The initiative demonstrated improved provider adherence to secondary prevention protocols.
Conclusions:
- Incidental CAC is frequently identified in patients without known CAD.
- Standardized guidelines and implementation strategies enhance secondary prevention of CAD.
- This approach optimizes care by improving provider prescribing behavior in primary care settings.
Abstract:
Background Coronary artery calcification (CAC), the presence and severity of which strongly predict underlying coronary artery disease (CAD), can be seen on dedicated cardiac imaging studies or incidentally on noncardiac ones; however, the latter findings are commonly managed by primary care clinicians without clear accompanying recommendations and may represent an underrecognized opportunity to optimize secondary prevention of CAD. Methods Standardized practice guidelines and a multilevel implementation strategy for improving secondary prevention of cardiovascular disease through incidentally identified CAC were developed by an interdisciplinary committee. Evidence-based implementation strategies were selected1 and included integrating practice guidelines into radiology reports within the electronic medical records. Outpatient noncardiac computerized tomography scans performed before and after this initiative were retrospectively reviewed to evaluate changes in statin prescribing. Results Authors demonstrated an increase in the percentage of patients with mild CAC prescribed a statin and an increase in the percentage of patients with severe CAC prescribed a high-intensity statin after implementation of standardized practice guidelines and evidence-based implementation strategies. Conclusion Incidental CAC identification is common, particularly in those without known CAD. A multilevel implementation strategy and use of standardized practice guidelines appeared to improve provider prescribing behavior in the primary care setting and may provide an opportunity to enhance secondary CAC prevention.
Related Concept Videos
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
Atherosclerosis III: Management
Coronary Artery Disease IV: Preventive Measures
Preventive Healthcare Services
Atherosclerosis IV: Nursing Management
Acute Coronary Syndrome IV: Interprofessional Care

