Related Experiment Video
Updated: Aug 2, 2025
11:31
Evaluation of the Storage Stability of Extracellular Vesicles
Published on: May 22, 2019
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Extracellular vesicles in vascular pathophysiology: beyond their molecular content
Ewa Ł Stępień1, Martyna Durak-Kozica2,3,4, Paweł Moskal2,3,4
1Marian Smoluchowski Institute of Physics, Jagiellonian University, Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland. e.stepien@uj.edu.pl
Polish Archives of Internal Medicine
|April 19, 2023
Summary
Extracellular vesicles (EVs) offer potential as biomarkers due to their molecular charge and composition. Their lipid and glycan components, along with electric charge, are crucial for understanding EV fate and clinical applications.
Area of Science:
- Cell biology
- Biochemistry
- Nanomedicine
Background:
- Extracellular vesicles (EVs) are released by cells under both normal and disease states.
- EVs possess molecular and compositional features that suggest biomarker potential.
- Beyond biomarkers, EVs have broader clinical applications.
Conclusions:
- EVs present multifaceted potential beyond biomarkers, owing to their complex composition.
- Understanding EV lipidomics and glycomics is essential for harnessing their therapeutic and diagnostic capabilities.
- EV electric charge represents a significant, underutilized factor for predicting and controlling EV behavior in vivo.
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