Related Experiment Video For Adenosquamous carinoma
Updated: Aug 2, 2025

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
Published on: August 9, 2016
A primary gastric Adenosquamous carcinoma: Case report
Christine Alsheikh1, AbdullahAladnan Aljammas1, Maan Nashar1
1Faculty of Medicine, University of Aleppo, Aleppo, Syria.
Introduction:
Adenosquamous carcinoma (ASC) is too rare accounting for <0.5 % of all gastric cancers and has a worse prognosis than adenocarcinoma.
Case Presentation:
We report a case of a man with digestive symptoms and epigastric discomfort came to a Gastrointestinal clinic. CT scan of the abdomen and pelvis showed a large mass localized in the gastric fundus and cardia. A PET-CT scan showed a localized lesion in the stomach. Gastroscopy revealed a mass in the gastric fundus. Biopsy from the gastric fundus reported a poorly-differentiated squamous cell carcinoma. A laparoscopic abdominal exploration found a mass and Infected Lymphatic Nodes on the abdomen wall. a second biopsy reported an Adenosquamous cell carcinoma grade II. The therapeutic was open surgery and then chemotherapy.
Clinical Discussion:
Adenosquamous carcinoma usually presents at an advanced stage with metastasis (Chen et al., 2015). In our case, the patient presented with a stage IV tumor; including two lymph nodes metastasis (pN1, N = 2/15) and abdominal wall involvement (pM1).
Conclusion:
Clinicians should be aware of this potential site of adenosquamous carcinoma (ASC) because this carcinoma has a poor prognosis even if diagnosed at an early stage.
