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Updated: Aug 2, 2025

Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
Role of open access echocardiography in detection of cardiac structural and functional abnormalities
Jason Chai1, Hasan Mohiaddin1, Amit K J Mandal1
1Department of Medicine and Cardiology, Wexham Park Hospital, Slough, UK.
Insights
Open access echocardiography detects significant heart disease in 27.3% of patients with cardiac symptoms referred by general practitioners. Early detection of conditions like heart failure and valve disease can improve cardiovascular outcomes.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- General practitioners (GPs) often encounter patients with cardiac symptoms.
- Timely diagnosis of structural heart disease is crucial for effective management.
- Open access echocardiography offers a potential pathway for early cardiac assessment.
Purpose of the Study:
- To determine the prevalence and incidence of significant structural heart disease in patients referred by GPs.
- To evaluate the utility of open access echocardiography in identifying cardiac abnormalities.
- To assess the rate of new diagnoses for conditions like left ventricular systolic dysfunction and cardiac valve disease.
Main Methods:
- A prospective study involving 488 patients referred by GPs for transthoracic echocardiography.
- Echocardiograms were performed within 4-6 weeks of referral via an online platform.
- Reports were reviewed by a consultant cardiologist to identify structural abnormalities, focusing on the left ventricle and valves.
Main Results:
- 27.3% of patients exhibited at least one abnormality requiring management changes.
- Heart failure with left ventricular systolic dysfunction (LVSD) was confirmed in 9% (33 new diagnoses).
- Diastolic dysfunction was found in 14%, and significant cardiac valve disease in 8.6% (30 new diagnoses).
Conclusions:
- Significant structural and functional cardiac abnormalities are prevalent in patients presenting to GPs with cardiac symptoms.
- Open access echocardiography facilitates early detection of cardiac pathology.
- Timely diagnosis and intervention can potentially improve cardiovascular outcomes.
Purpose:
To evaluate the prevalence and incidence of significant structural heart disease in targeted patients with cardiac symptoms referred by general practitioners (GPs) using open access echocardiography, without prior clinical evaluation by a cardiologist.
Design:
Data were derived from 488 subjects who underwent transthoracic echocardiography between January and April 2018. Patients were referred directly by GPs in East Berkshire, South England, through an online platform. Echocardiography was performed within 4-6 weeks of referral and all reports were assessed by a consultant cardiologist with expedited follow-up facilitated pro re nata. Results were analysed to determine the frequency of detection of structural abnormalities, particularly of the left ventricle and cardiac valves.
Results:
Echocardiography was prospectively performed in consecutive subjects (50% male, mean (±SD) age 68.5±22 years; 50% female; mean (±SD) 64.6 (±19.1)). At least one abnormality likely to change management was found in 133 (27.3%) of all open access echocardiograms. Clinical heart failure with left ventricular systolic dysfunction (LVSD) and diastolic dysfunction was confirmed in 46 (9%) and 69 (14%), respectively. Of the 46 patients with LVSD, 33 were new diagnoses. Significant cardiac valve disease was found in 42 (8.6%) patients. 12 of these had known valvular disease or previous valvular surgery, and 30 were new diagnoses.
Conclusion:
Major structural and functional cardiac abnormalities are common in late middle-aged patients who present to GPs with cardiac symptoms and signs. Reported, unrestricted open access echocardiography enables early detection of significant cardiac pathology and timely intervention may improve cardiovascular outcomes.
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