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Updated: Aug 2, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.3K

Structural MRI in Migraine: A Review of Migraine Vascular and Structural Changes in Brain Parenchyma

Wilson J Xu1, Giuseppe Barisano1,2, Daniel Phung1

  • 1Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Journal of Central Nervous System Disease
|April 20, 2023
PubMed

Insights

Structural MRI reveals brain changes in migraine patients, offering insights into pathophysiology. This review explores imaging findings to improve migraine diagnosis and treatment.

Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • Migraine is a prevalent neurological disorder with complex pathophysiology.
  • Current understanding of migraine mechanisms remains incomplete.
  • Structural Magnetic Resonance Imaging (MRI) has identified brain alterations in migraineurs.

Purpose of the Study:

  • To review structural MRI findings in various migraine types.
  • To correlate imaging findings with migraine characteristics and subtypes.
  • To enhance understanding of migraine pathophysiology, diagnosis, and treatment.

Main Methods:

  • Systematic review of structural MRI studies in migraine.
  • Analysis of imaging findings such as white matter lesions, volume changes, and iron deposition.
  • Correlation of neuroimaging data with clinical migraine features.

Main Results:

  • Structural MRI reveals diverse brain parenchyma changes in migraine.
  • Observed changes include white matter lesions, altered brain volumes, and iron accumulation.
  • These findings vary across different migraine subtypes and characteristics.

Conclusions:

  • Structural MRI provides valuable insights into migraine pathophysiology.
  • Imaging biomarkers can aid in understanding migraine heterogeneity.
  • Further research can optimize diagnosis and treatment strategies for migraine.
Keywords:
Headache disorderscentral nervous systemmigrainepain

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