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Updated: Aug 2, 2025
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Next-generation Sequencing of 16S Ribosomal RNA Gene Amplicons
Published on: August 29, 2014
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Novel and Efficient Method for Diagnosing Infective Endocarditis Using 16S Ribosomal RNA Gene Amplicon Sequence
Akihisa Kataoka1, Takahiko Shiba2,3, Sayaka Katagiri2
1Department of Medicine, Division of Cardiology, Teikyo University, Tokyo, Japan.
JACC. Case Reports
|April 20, 2023
Abstract:
We present 2 cases that both developed infective endocarditis and underwent mitral valve replacement. In addition to positive blood culture and echocardiographic findings, such as vegetation or mitral valve perforation, the 16S ribosomal RNA gene amplicon sequence approach used was helpful for disease diagnosis. (Level of Difficulty: Intermediate.).
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