Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

STAT6/LINC01637 axis regulates tumor growth via autophagy and pharmacological targeting STAT6 as a novel strategy for uveal melanoma.

Cell death & disease·2024
Same author

Reduced contrast sensitivity function correlated with superficial retinal capillary plexus impairment in early stage of dysthyroid optic neuropathy.

Eye and vision (London, England)·2023
Same author

LINC01278 Induces Autophagy to Inhibit Tumour Progression by Suppressing the mTOR Signalling Pathway.

Oxidative medicine and cellular longevity·2023
Same author

PTK6 inhibits autophagy to promote uveal melanoma tumorigenesis by binding to SOCS3 and regulating mTOR phosphorylation.

Cell death & disease·2023
Same author

Retinal peripapillary microvasculature in indirect traumatic optic neuropathy predicted prognosis of endoscopic trans-ethmosphenoid optic canal decompression.

Acta ophthalmologica·2022
Same author

The change of microglia numbers within the mice retina, optic nerve and chiasm following intravitreal AAV2-GFP injection.

European journal of ophthalmology·2021

Related Experiment Video

Updated: Aug 2, 2025

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering
10:17

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

Published on: May 16, 2022

2.3K

Biomaterial-Based bFGF Delivery for Nerve Repair.

Qinying Huang1,2, Bo Liu1,2, Wencan Wu1,2

  • 1State Key Laboratory of Ophthalmology, Optometry and Vision Science, Wenzhou Medical University, Wenzhou, China.

Oxidative Medicine and Cellular Longevity
|April 20, 2023
PubMed
Summary

Biomaterials enhance the stability of basic fibroblast growth factor (bFGF) for improved nerve repair. This review explores biomaterial applications for sustained bFGF delivery to treat nervous system diseases.

More Related Videos

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

14.8K
Designing Porous Silicon Films as Carriers of Nerve Growth Factor
10:12

Designing Porous Silicon Films as Carriers of Nerve Growth Factor

Published on: January 25, 2019

9.8K

Related Experiment Videos

Last Updated: Aug 2, 2025

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering
10:17

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

Published on: May 16, 2022

2.3K
Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

14.8K
Designing Porous Silicon Films as Carriers of Nerve Growth Factor
10:12

Designing Porous Silicon Films as Carriers of Nerve Growth Factor

Published on: January 25, 2019

9.8K

Area of Science:

  • Neuroscience
  • Biomaterials Science
  • Regenerative Medicine

Background:

  • Nervous system diseases impose significant burdens due to high costs and poor prognoses.
  • Basic fibroblast growth factor (bFGF) is vital for tissue homeostasis, regulating cell proliferation, differentiation, and repair.
  • Improving bFGF stability is crucial for enhancing treatment efficacy in various diseases.

Purpose of the Study:

  • To review biomaterials used for basic fibroblast growth factor (bFGF) delivery for nerve repair.
  • To elucidate the function of delivered bFGF within the nervous system.
  • To provide guidance for future research on nerve injury using bFGF.

Main Methods:

  • Literature review of studies employing biomaterials for bFGF delivery.
  • Analysis of bFGF's role in neural tissue regeneration.
  • Synthesis of information on biomaterial-based sustained release systems.

Main Results:

  • Biomaterials offer a biocompatible approach to stabilize and deliver bFGF.
  • Sustained local delivery of bFGF via biomaterials promotes nerve repair.
  • Various biomaterial types are effective for bFGF loading and controlled release.

Conclusions:

  • Biomaterial-mediated bFGF delivery is a promising strategy for treating nerve injuries.
  • Further research is needed to optimize biomaterial-bFGF systems for clinical application.
  • This review offers a framework for future studies in bFGF-based nerve regeneration.