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Published on: September 11, 2021
Exploration of the thoracoscopic treatment of esophageal atresia under high-frequency ventilation
Chao Zheng1,2, Yu Lin1,2, Yuanbin He1,2
1Department of Pediatric Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), Fuzhou, China.
Insights
Thoracoscopic esophageal atresia repair is feasible with high-frequency oscillatory ventilation (HFOV), showing shorter operation times. This approach benefits patients with complex conditions, though long-term outcomes require further investigation.
Area of Science:
- Pediatric Surgery
- Thoracic Surgery
- Critical Care Medicine
Background:
- Esophageal atresia (EA) repair presents surgical challenges, particularly in neonates with comorbidities.
- High-frequency oscillatory ventilation (HFOV) is used in pediatric respiratory distress but its role during EA surgery is less defined.
Purpose of the Study:
- To evaluate the feasibility and safety of thoracoscopic EA repair performed under HFOV.
- To compare surgical outcomes between EA repair with and without HFOV.
Main Methods:
- A single-center retrospective analysis of 24 children undergoing EA repair.
- Patients were divided into HFOV and non-HFOV groups.
- Demographic data, surgical results, and complications were analyzed.
Main Results:
- Thoracoscopic EA repair under HFOV was feasible, with a mean operative time of 165.8 minutes.
- Postoperative complications included two cases of anastomotic leakage and one recurrent tracheoesophageal fistula, all managed conservatively.
- Mean mechanical ventilation time was 8.83 days; no significant differences were found between groups except for shorter operative time in the HFOV group.
Conclusions:
- Thoracoscopic EA anastomosis under HFOV is feasible, especially for patients with severe pulmonary infections, cardiac malformations, or poor anesthesia tolerance.
- While short-term outcomes appear favorable, long-term prognosis necessitates further large-scale studies.
Objective:
Explore the feasibility and safety of thoracoscopy in the treatment of esophageal atresia under high-frequency oscillatory ventilation (HFOV) mode.
Methods:
This was a single-center retrospective analysis. A total of 24 children were divided into the HFOV and the No-HFOV group. The demographic information, surgical results and relevant experience were analyzed.
Results:
All patients in the HFOV group underwent thoracoscopic esophageal atreplasty with a mean operation duration of 165.8 ± 33.9 min. Two patients had postoperative anastomotic leakage, which was cured after conservative treatment. One child had a recurrent tracheoesophageal fistula, which was closed after endoscopic cauterization. The mean postoperative mechanical ventilation time was 8.83 ± 8.02 days. There was no return of anastomotic leakage or r-TEF after oral feeding. Furthermore, there was no significant difference between the NO-HFOV and the HFOV groups except for the operation time where the HFOV group was shorter than that of the NO-HFOV group.
Conclusion:
Thoracoscopic esophageal atresia anastomosis under HFOV ventilation is feasible for patients with severe pulmonary infection, heart malformation, such as patent ductus arteriosus, ventricular septal defect, and poor anesthesia tolerance, but the long-term prognosis still needs further study in a large sample size.
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