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Extrafibrillar proteoglycans osmotically regulate the molecular packing of collagen in cartilage

E P Katz, E J Wachtel, A Maroudas

Biochimica Et Biophysica Acta

|June 3, 1986

Abstract:

The molecular packing density of collagen and hence the intrafibrillar water content appears to be regulated in cartilage by the osmotic pressure gradient existing between the extrafibrillar and the intrafibrillar compartments.

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