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Related Experiment Video

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The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
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Sarcopenia in youth.

Han Na Jung1, Chang Hee Jung2, You-Cheol Hwang3

  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang-si, Gyeonggi-do, Republic of Korea.

Metabolism: Clinical and Experimental
|April 20, 2023
PubMed
Summary
This summary is machine-generated.

Sarcopenia, or muscle loss, can affect young adults due to factors beyond aging. Early intervention is crucial as over 1 in 10 young adults may be impacted by this condition.

Keywords:
AdolescentMuscle massMuscle strengthSarcopenia

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Area of Science:

  • Gerontology
  • Muscle Physiology
  • Nutritional Science

Background:

  • Sarcopenia, typically associated with aging, is increasingly recognized in younger populations.
  • Youth-onset sarcopenia poses risks for future muscle dysfunction.
  • Research on sarcopenia in young adults is limited, with challenges in prevalence estimation.

Purpose of the Study:

  • To review the current knowledge on the importance, prevalence, diagnosis, and causes of sarcopenia in youth.
  • To highlight emerging non-aging related etiologies of sarcopenia in young individuals.

Main Methods:

  • Systematic review of existing literature on youth-onset sarcopenia.
  • Analysis of epidemiological data and diagnostic criteria for sarcopenia in young populations.
  • Synthesis of evidence on various potential causes of sarcopenia in youth.

Main Results:

  • Sarcopenia risk begins in early adulthood, potentially leading to severe muscle dysfunction later in life.
  • An estimated prevalence of over 10% of young adults across most ethnicities are affected by sarcopenia.
  • Identified potential etiologies include metabolic syndrome, physical inactivity, poor nutrition, vitamin D deficiency, and inflammatory disorders.

Conclusions:

  • Sarcopenia is a significant concern in young adults, with diverse underlying causes.
  • Further research and standardized diagnostic criteria are needed to address youth-onset sarcopenia.
  • Understanding the multifactorial nature of sarcopenia in youth is essential for timely intervention.