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Historical Advances in Structural and Molecular Biology and How They Impacted Vaccine Development
Wayne C Koff1, Rino Rappuoli2, Stanley A Plotkin3
1Human Immunome Project, New York, NY, USA. Electronic address: https://twitter.com/ImmunomePro.
Vaccine development leverages advances in genomics and structural biology to combat infectious diseases and cancers. New technologies like mRNA vaccines accelerate the creation of innovative and improved preventative health tools.
Area of Science:
- Immunology
- Genomics
- Structural Biology
- Vaccinology
Background:
- Vaccines are critical for preventing and controlling infectious diseases, eradicating smallpox, and reducing the impact of polio, measles, and COVID-19.
- Vaccines also play a role in preventing viral-induced cancers, such as cervical cancer caused by human papillomavirus.
- Technological progress in genomics, structural biology, and immunology has revolutionized vaccine development.
Conclusions:
- Vaccine development is an evolving field, significantly enhanced by modern scientific and technological breakthroughs.
- Continued innovation in areas like genomics and structural biology promises further advancements in preventing and controlling diseases.
- The review underscores the profound impact of vaccines on global public health.
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