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Non-ST-Segment Elevation Myocardial Infarction As Initial Thrombotic Event of Thrombotic Thrombocytopenic Purpura: A

Khalid H Mohamed1, Saher T Shiza2, Iqra Samreen2

  • 1Neurology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, GBR.

Cureus
|April 21, 2023
PubMed

Thrombotic thrombocytopenic purpura (TTP) is a rare autoimmune and devastating blood disorder that results in micro-clots throughout the body, leading to tissue damage and organ dysfunction resulting in widespread microangiopathic hemolytic anemia, thrombocytopenia, fever, and neurological symptoms. TTP patients commonly manifest renal and neurological symptoms; however, cardiovascular involvement is not widely reported in the literature. We report a case of non-ST-segment elevation myocardial infarction (NSTEMI) as an initial manifestation of TTP. Although rare, TTP complications must be considered among other possible causes of unexpected thrombocytopenia during acute phase treatment of acute coronary syndrome because of high morbidity and mortality.

Keywords:
acquired ttpacute coronary syndromemyocardial infarctionthrombotic microangiopathiesthrombotic thrombocytopenic purpura

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