Aggregation-Induced Emission Macromolecular Materials for Antibacterial Applications
Yunfei Zuo1, Ryan T K Kwok1, Jianwei Sun1
1Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, and Division of Life Science, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, 999077, P.R. China.
Abstract:
Recent advancements in aggregation-induced emission (AIE) macromolecular materials have brought their attention as potential antibacterial solutions, these materials offer new approaches to cure multidrug-resistant infections and biofilms in bacterial infections as well as real-time monitoring and specific targeting of bacteria. This review provides an overview of the three main categories of AIE macromolecular materials with antibacterial properties; namely AIE-active polymers, AIEgen@polymer complexes, and clusterization-triggered emission (CTE) based polymers. The mechanisms and applications of these materials in antibacterial treatment, wound care, and protective equipment are also discussed. The potential for future developments and application directions of AIE-based antimicrobial materials are finally highlighted.
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