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Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

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The Treat-to-Target Project in Atopic Dermatitis: One Year On.

Marjolein De Bruin-Weller¹, Mette Deleuran², Tilo Biedermann³

¹Department of Allergology and Dermatology, UMC Utrecht, National Expertise Center for Eczema, Utrecht, The Netherlands. m.s.debruin-weller@umcutrecht.nl.

Acta Dermato-Venereologica

|April 21, 2023

Summary

This summary is machine-generated.

New systemic treatments for atopic dermatitis (AD) are available. This review examines the current treat-to-target strategy and management algorithm for AD, considering recent therapeutic advancements and suggesting areas for improvement.

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Area of Science:

Dermatology
Immunology
Pharmacology

Background:

Atopic dermatitis is a chronic inflammatory skin disease.
Recent approvals of systemic treatments have expanded therapeutic options.
A treat-to-target strategy and management algorithm previously guided AD care.

Purpose of the Study:

To review the existing treat-to-target strategy and management algorithm for atopic dermatitis.
To contextualize these guidelines within the evolving landscape of systemic therapies.
To identify areas needing refinement and future development in AD management.

Main Methods:

Literature review of recent systemic treatments for atopic dermatitis.
Analysis of the current treat-to-target strategy and management algorithm.
Synthesis of information to identify gaps and areas for improvement.

Main Results:

The therapeutic landscape for atopic dermatitis has significantly evolved with new systemic agents.
The existing strategy and algorithm require updates to incorporate these advancements.
Specific areas for refinement in patient management have been identified.

Conclusions:

The current treat-to-target strategy and algorithm for atopic dermatitis need adaptation.
Integration of newly approved systemic treatments is crucial for optimal patient outcomes.
Further research and guideline development are necessary to refine atopic dermatitis management.