Multimodality imaging features of parosteal lipomas
Akriti Khanna1, Nathan L Eickstaedt2, Doris E Wenger1,3
1Department of Radiology, Mayo Clinic, Charlton Building North, 1st Floor, 200 First Street SW, Rochester, MN, 55905, USA.
Skeletal Radiology
|April 21, 2023
Summary
Parosteal lipomas are rare benign tumors. Multimodality imaging reveals characteristic features, potentially eliminating the need for biopsy in diagnosing these fatty tumors.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Parosteal lipomas are uncommon benign tumors.
- They are characterized by a fatty component and an osseous excrescence.
- Accurate diagnosis is crucial for appropriate management.
Purpose of the Study:
- To investigate the multimodality imaging features of parosteal lipomas.
- To identify characteristic imaging findings that aid in diagnosis.
- To assess the utility of imaging in differentiating parosteal lipomas from other lesions.
Main Methods:
- Retrospective review of imaging database and medical records (1990-2020).
- Inclusion of pathologically-proven and/or imaging-diagnosed parosteal lipomas.
- Analysis of imaging characteristics across various modalities.
Main Results:
- 22 patients (mean age 57.1 years) with parosteal lipomas identified.
- Common locations include femur and forearm.
- Key imaging findings: juxtacortical fatty mass with osseous excrescence, cortical thickening/periostitis.
- Osseous excrescences showed mature bone or bone spicules; fatty portions contained non-lipomatous elements in 59% of cases.
- Bone scan showed uptake; FDG PET/CT showed no uptake in limited cases.
Conclusions:
- Parosteal lipomas possess distinctive multimodality imaging features.
- These pathognomonic features can potentially obviate the need for biopsy.
- Imaging plays a vital role in the non-invasive diagnosis of parosteal lipomas.


