Drug treatment of changes in platelet-vessel wall interactions in burned rats

The interaction between blood platelets and the walls of blood vessels is changed after burn injury to rats and guinea-pigs. Treatment of burned experimental animals with heparin, nicotinic acid, thrental, phytin, glutamic acid and alpha-tocopherol inhibited the increase in platelet-vascular wall interaction, improved the microcirculation in mesenteric vessels and increased the endurance of the animals to physical stress.