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Updated: Aug 2, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
A Multidisciplinary Approach to Infants With GERD-Like Symptoms: A New Paradigm
Mark H Fishbein1, Jessica Kronberg2, Stephanie Alvarado3
1From Feinberg School of Medicine at Northwestern University, Chicago, IL.
Insights
Many infants with GERD-like symptoms actually have dysphagia or colic. A multidisciplinary evaluation by speech-language pathologists and occupational therapists is recommended for accurate diagnosis and treatment.
Area of Science:
- Pediatrics
- Gastroenterology
- Developmental Pediatrics
Background:
- Gastroesophageal reflux disease (GERD)-like symptoms in infants are often misdiagnosed.
- Anti-reflux medications are frequently ineffective and overprescribed for these symptoms.
- Symptoms may be more accurately attributed to dysphagia and unsettledness/colic.
Purpose of the Study:
- To investigate the prevalence of dysphagia and unsettledness/colic in infants presenting with GERD-like symptoms.
- To evaluate the effectiveness of a multidisciplinary approach involving speech-language pathologists (SLP) and occupational therapists (OT).
Main Methods:
- A cohort of 174 full-term infants under 6 months with typical development was studied.
- Infants with suspected dysphagia or colic/unsettledness underwent evaluation by SLP and OT, respectively.
Main Results:
- Out of 109 infants with GERD-like symptoms, 46 had dysphagia, 37 had unsettledness/colic, and 26 had both.
- These findings suggest a high prevalence of these under-recognized conditions.
Conclusions:
- A multidisciplinary approach involving SLP and OT is crucial for evaluating infants with GERD-like symptoms.
- Accurate diagnosis of dysphagia and colic can lead to more appropriate management.
Objectives:
Infants with gastroesophageal reflux disease (GERD)-like symptoms have been classically defined as having a wide array of symptoms. In these instances, anti-reflux medications are ineffective and overprescribed. Rather these symptoms are more attributable to dysphagia and unsettledness/colic. To address these conditions at our center, both speech language pathologist (SLP) and/or occupational therapist (OT) have contributed to evaluation. We hypothesized that dysphagia and unsettledness/colic are highly prevalent, yet under recognized in this population.
Methods:
Full-term infants with typical development and under 6 months of age (N = 174) were included. Infants with suspected dysphagia and/or evident colic/unsettledness were evaluated by SLP and OT, respectively.
Results:
GERD-like symptoms were present in 109 infants with attributes of dysphagia in n = 46, unsettledness/colic in n = 37, and combined in n = 26.
Conclusion:
A multidisciplinary approach, including SLP and OT, is recommended for the evaluation of infants with GERD-like symptoms.
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