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Updated: Aug 2, 2025

Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition
Published on: February 1, 2012
[Imaging of brain activity using fMRI in a patient with subjective cognitive decline]
E Yu Solovieva1, O V Vorob'eva2, V V Fateeva2,3
1Pirogov Russian National Research Medical University, Moscow, Russia.
Abstract:
In clinical practice, subjective cognitive decline (SCD) is often difficult to diagnose because it is not detected by standard neuropsychological and cognitive tests.The described clinical case is presented to demonstrate the difficulties of diagnosis and treatment choice in a patient with SCD. fMRI might be considered as an instrumental method to analyze the functional relationship between the activity of brain structures and cerebral circulation in patients with SCD. Patient clinical and neuropsychological data with a detailed description of fMRI with a cognitive paradigm are presented. The article is focused on the early diagnosis of SCD and the prognostic assessment of the transition of SCD to dementia.
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