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Comprehensive commissioning and quality assurance validation of Ethos™ therapy
A Morel1, J Prunaretty1, D Trauchessec1
1Institut du cancer de Montpellier (ICM), Montpellier, France.
Summary
Commissioning of the Ethos® therapy Varian system, including beam data and treatment planning, was successfully validated. This ensures accurate and reliable adaptive radiotherapy delivery for patient treatment.
Area of Science:
- Radiation Oncology
- Medical Physics
- Radiotherapy Technology
Background:
- Adaptive radiotherapy (ART) offers personalized cancer treatment.
- The Ethos® therapy Varian system represents a new advancement in ART.
- Rigorous commissioning is essential for implementing new radiotherapy systems.
Purpose of the Study:
- To detail the commissioning process for the Ethos® therapy Varian system.
- To validate the system's beam data, treatment planning algorithms, and patient quality assurance (QA) protocols.
- To ensure the safe and effective implementation of adaptive radiotherapy.
Main Methods:
- Validated machine golden beam data using percentage depth doses (PDD) and profiles measured with a microdiamond chamber.
- Compared dose calculations from Ethos Acuros XB (AXB) and Eclipse Analytic Anisotropic Algorithm using gamma index.
- Assessed patient QA by comparing Mobius3D and Epiqa portal dosimetry results.
Main Results:
- Minor differences in PDD (0.2%) and profiles (2%) were observed.
- Gamma index pass rates exceeded 98% for PDD and profile evaluations.
- Ethos AXB algorithm and patient QA showed excellent agreement with TPS calculations (>99% gamma index).
Conclusions:
- The beam delivery, Ethos AXB algorithm, and patient QA were comprehensively validated.
- Independent tools confirmed the system's readiness for clinical implementation.
- The commissioning process ensures the reliable delivery of adaptive radiotherapy.
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