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Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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The mechanism of STING autoinhibition and activation

Sheng Liu1, Bo Yang2, Yingxiang Hou3

  • 1Shanxi Provincial Key Laboratory of Protein Structure Determination, Shanxi Academy of Advanced Research and Innovation, Taiyuan 030012, China; CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Cryo-EM Center, Southern University of Science and Technology, Shenzhen 518055, China.

Molecular Cell
|April 22, 2023
PubMed

Keywords:
STINGactivationautoinhibitioncGAMPcGAS

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