Related Experiment Videos
TPP+ inhibits Na+-stimulated Ca2+ efflux from brain mitochondria
Cell Calcium
|April 1, 1986
Abstract:
Tetraphenylphosphonium (TPP+) inhibits Na+-stimulated Ca2+ efflux from brain mitochondria. Half inhibition is observed when 1.10(-8)M TPP+ is present in the medium. Some other lipophylic cations show similar effect. TPP+ must be used carefully for measuring transmembrane potential because of its effects on the system studied. TPP+ will be a useful tool to study Ca-transport system in mitochondria.