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Updated: Aug 2, 2025

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
Published on: May 17, 2024
Long-term outcomes for children conceived by assisted reproductive technology
Anja Pinborg1, Ulla-Britt Wennerholm2, Christina Bergh2
1Department of Fertility, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark; Instistute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Over 10 million children worldwide are born via assisted reproduction technology (ART). This review examines the long-term health outcomes for these children, considering factors related to fertility and ART procedures.
Area of Science:
- Reproductive Medicine
- Pediatric Health
- Genetics
Background:
- Assisted reproduction technology (ART) has resulted in over 10 million births globally.
- ART-born children show higher rates of preterm birth, low birth weight, and birth defects.
- Long-term health data for ART-born children are limited but suggest potential cardiovascular risks.
Conclusions:
- ART-born children face specific short-term health risks.
- Long-term health implications require further investigation.
- Future ART developments must prioritize maternal and child safety.
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