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Penetration of ciclacillin into bronchial secretions
Chemioterapia : International Journal of the Mediterranean Society of Chemotherapy
|April 1, 1986
Abstract:
The penetration of ciclacillin into bronchial secretions was investigated in 105 patients undergoing bronchoscopy after a single oral dose of 500 mg ciclacillin. Comparison was made with 26 patients who received 500 mg ampicillin by mouth. Over a 6 to 8 hour period, ciclacillin achieved significantly higher levels in bronchial secretions but no statistically significant difference between serum ampicillin and ciclacillin levels was detected.