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Comparison Between Simultaneous and Sequential Utilization of Safety and Efficacy for Optimal Dose Determination in

Ran Li1, Kentaro Takeda2, Alan Rong2

  • 1Biostatistics, Data Science, Astellas Pharma Inc, 1 Astellas Way, N3.272.A, Northbrook, IL, 60062, USA. ran-li@astellas.com.

Therapeutic Innovation & Regulatory Science
|April 22, 2023
PubMed

Keywords:
Bayesian adaptive dose-finding designExpansion cohortOncologyOptimal doseSeamless designSequential enrollment

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