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Published on: July 24, 2013
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Relationship between lower urinary tract symptoms and frailty
Yusuke Ozaki1, Shingo Hatakeyama2, Atsushi Imai1
1Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Summary
Lower urinary tract symptoms (LUTS) significantly worsened over five years, with frailty measures also changing. The study suggests LUTS may impact frailty more than frailty impacts LUTS.
Area of Science:
- Gerontology
- Urology
- Public Health
Background:
- Frailty and lower urinary tract symptoms (LUTS) are common in older adults.
- Understanding their relationship is crucial for geriatric care.
Purpose of the Study:
- To investigate the longitudinal relationship between frailty and LUTS in community-dwelling older adults.
- To determine the directionality of the association between frailty and LUTS.
Main Methods:
- Longitudinal study of 247 adults (≥45 years) with 5-year follow-up.
- Frailty assessed using Fried phenotype, 5-item modified frailty index (5i-mFI), and frailty discriminant score.
- LUTS evaluated with International Prostate Symptom Score (IPSS) and Overactive Bladder Symptom Score (OABSS).
Main Results:
- Median IPSS and OABSS significantly increased over 5 years.
- The 5i-mFI score significantly increased, indicating worsening comorbidity-based frailty.
- The 5i-mFI score in 2019 was associated with LUTS severity in 2014, but not vice versa.
Conclusions:
- The impact of LUTS on frailty may be more significant than the impact of frailty on LUTS.
- Further large-scale research is warranted to fully elucidate this complex relationship.
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