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Tiratricol, a thyroid hormone metabolite, has potent inhibitory activity against human dihydroorotate dehydrogenase

Shuying Cao1, Hui Ma1, Zhaomin Xu1

  • 1Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China.

Chemical Biology & Drug Design
|April 23, 2023
PubMed

Keywords:
ThermoFMN assayhuman dihydroorotate dehydrogenasemolecular dockingsite-directed mutagenesistiratricol

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