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Granulocyte-dependent Autoantibody-induced Skin Blistering
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Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review
Madiha Khan1, Lily Park2,3, Stanley Skopit2
1Department of Dermatology, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, USA.
Abstract:
Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is an autoimmune condition with various triggers. Because of the lack of randomized controlled trials on LABD treatment, management options are mostly anecdotal. This paper provides a comprehensive review of treatment options from a literature review of reported treatments to arm clinicians with a guideline for the management of LABD in both pediatric and adult patients as well as those recalcitrant to first-line therapy (dapsone and steroids). We additionally illustrate an algorithm to use for the management of LABD to aid clinicians when faced with unique patient circumstances.
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