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The extrathoracic airway in acromegaly
Clinical Radiology
|May 1, 1986
Summary
Patients with acromegaly often experience upper-airway obstruction and laryngeal narrowing. These findings highlight the importance of pulmonary function tests and radiological assessment for identifying patients at risk during general anesthesia.
Area of Science:
- Endocrinology
- Pulmonology
- Radiology
Background:
- Acromegaly, a condition caused by excess growth hormone, can affect various organs.
- The impact of acromegaly on the larynx and trachea requires further investigation.
Purpose of the Study:
- To assess airway abnormalities in patients with acromegaly using pulmonary function tests and radiological imaging.
- To determine if acromegaly leads to significant changes in laryngeal and tracheal dimensions.
Main Methods:
- Pulmonary function tests were conducted on 26 acromegaly patients.
- Laryngeal tomography and tracheal assessment were performed.
- Statistical analysis (Mann-Whitney U-test) compared patient and control groups.
Main Results:
- Six patients showed upper-airway obstruction on pulmonary function tests.
- Fourteen patients exhibited laryngeal narrowing (true and false cords).
- Increased true and false cord thickness was observed in acromegaly patients compared to controls. Male patients showed decreased transverse tracheal diameter.
Conclusions:
- Pulmonary function tests and radiological assessment are valuable tools for identifying acromegaly patients with potential airway complications.
- Acromegaly is associated with laryngeal thickening and potential upper-airway obstruction, increasing risks during general anesthesia.