Contact allergy to hydrocortisone and thixocortol pivalate: problems in the detection of corticosteroid sensitivity

Several of the difficulties involved in the detection of corticosteroid allergy are illustrated by the problems encountered in a patient sensitive to a preparation containing hydrocortisone and miconazole nitrate. The importance of appropriate concentrations and vehicles for patch testing, the possible rôle of impurities, and cross-sensitivity of corticosteroid molecules are discussed.