A deep dive into future therapies for microcytic anemias and clinical considerations
François Rodrigues1,2, Tereza Coman2,3, Guillemette Fouquet1,4
1Université de Paris, service d'hématologie adultes, Hôpital Necker - Enfants Malades, France.
Introduction:
Microcytic anemias (MA) have frequent or rare etiologies. New discoveries in understanding and treatment of microcytic anemias need to be reviewed.
Areas Covered:
Microcytic anemias with a focus on the most frequent causes and on monogenic diseases that are relevant for understanding biocellular mechanisms of MA. All treatments except gene therapy, with a focus on recent advances. PubMed search with references selected by expert opinion.
Expert Opinion:
As the genetic and cellular backgrounds of dyserythropoiesis will continue to be clarified, collaboration with bioengineering of treatments acting specifically at the protein domain level will continue to provide new therapies in hematology as well as oncology and neurology.
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