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Recent advances in polygalacturonase: Industrial applications and challenges
Siyi Liu1, Linfang Tian1, Yuting Cong1
1College of Fisheries and Life Science, Dalian Ocean University, Dalian, 116023, China; Engineering Research Center of Shellfish Culture and Breeding in Liaoning Province, Dalian, 116023, China; Key Laboratory of Environment Controlled Aquaculture, Ministry of Education, Dalian, 116023, China.
Carbohydrate Research
|April 24, 2023
Summary
This review explores polygalacturonase (PG) enzyme applications across industries. It highlights the need for improved thermostable PGs for industrial biocatalysis, offering guidelines for enzyme modification and resource mining.
Area of Science:
- Enzymology
- Industrial Biotechnology
- Biocatalysis
Background:
- Polygalacturonase (PG) is a commercially significant enzyme used across various industries.
- Current acidic mesophilic PGs exhibit limitations in industrial application effectiveness.
- There is a growing demand for alkaline, heat-resistant PGs driven by biomanufacturing advancements.
Conclusions:
- Thermophilic PGs hold significant potential for industrial biocatalysis.
- Molecular engineering is key to developing robust PGs for demanding applications.
- This review offers a framework for advancing heat-resistant PG development.

