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Updated: Aug 1, 2025

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
Original article - Effect of different resistance training intensities on endothelial function in people with type 2
Thiago Borges Madureira Sabino1, Denise Maria Martins Vancea2, Manoel da Cunha Costa3
1Federal University of Pernambuco, Graduate Program in Physical Education Recife, Brazil.
Aims:
The objective of this systematic review was to analyze the effects of different resistance training (RT) intensities compared with group control (GC) or control conditions (CON) on endothelial function (EF) in people with type 2 diabetes mellitus (T2DM).
Methods:
Seven electronic databases were searched Pubmed, Embase, Cochrane, Web of Science, Scopus, PEDro and CINAHL) until February 2021.
Results:
This systematic review retrieved a total of 2,991 studies of which 29 articles fulfilled the eligibility criteria. Four studies were included in the systematic review compared RT intervention with GC or CON. One study demonstrated an increase in blood flow-mediated dilation (FMD) of the brachial artery immediately after (95% CI: 3.0% to 5.9%; p < 0.05), 60 min after (95% CI: 0.8 % to 4.2%; p < 0.05) and 120 min after (95%CI: 0.7% to 3.1%; p < 0.05) a single high-intensity resistance training session (RPE ∼ 5 "hard"), compared to the control condition. Nevertheless, this increase was not significantly demonstrated in three longitudinal studies (more than 8 weeks).
Conclusions:
This systematic review suggest that a single session of high-intensity resistance training improves the EF of people with T2DM. More studies are needed to establish the ideal intensity and effectiveness for this training method.

