Related Experiment Video
Updated: Aug 1, 2025
05:10
Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
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Knowledge Mapping of Drug Repositioning's Theme and Development
Xiaona Lang1, Jinlei Liu2, Guangzhong Zhang3
1Pharmacy Department, Tianjin Hospital, Tianjin, People's Republic of China.
Drug Design, Development and Therapy
|April 25, 2023
Summary
Drug repositioning accelerates new drug development for emerging diseases. Bibliometric analysis reveals key research trends like molecular docking and machine learning, highlighting the need for increased support in this field.
Area of Science:
- Pharmacology
- Biotechnology
- Computational Chemistry
Background:
- Rising demand for novel therapeutics due to new and resistant diseases.
- Drug repositioning offers a viable strategy to meet these demands.
- Bibliometric analysis provides insights into current research landscape.
Purpose of the Study:
- To analyze research foci and trends in drug repositioning.
- To identify key methodologies and emerging areas within the field.
- To predict future development trajectories of drug repositioning research.
Main Methods:
- Bibliometric analysis of literature from 2001-2022.
- Data collection from Web of Science database.
- Visualization and analysis using CiteSpace and bibliometric platforms.
Main Results:
- Significant increase in publication quality and quantity post-2011.
- High citation counts for influential articles and international collaborations.
- Core research areas identified: molecular docking, virtual screening, drug discovery, machine learning, and drug-target interaction.
Conclusions:
- Drug repositioning focuses on discovering new indications for existing drugs.
- This approach saves time and resources in drug development.
- Increased financial and technical support is crucial for advancing drug repositioning.
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